Table of Contents
In 2009, the Mercedes-Benz S-Class underwent a facelift, which debuted in Stuttgart in April. This article provides detailed fuse box diagrams and relay assignments for facelifted Mercedes-Benz W221 / C216 (5th Gen S-Class: S350, S450, S500, S63 AMG, S65 AMG) models produced from 2009 through 2013.
Below you will find fuse box locations, layout diagrams, and photos. Fuses responsible for the “Cigarette Lighter” and “Fuel Pump” circuits are highlighted in bold.
Trunk Fuse Box Location
Access is gained from the passenger compartment. Fold down the center armrest, then remove the trim panel and protective plastic cover.
Access procedure.
Fuse box overview.
| Diagram | ||
|---|---|---|
|
||
| No. | Relay Designation | |
| M | Terminal 15 (2) / Spare 1 (changeover relay) | |
| N | Terminal 15R relay | |
| O | Power outlets relay | |
| P | Heated rear window relay | |
| Q | Engines 156, 157, 275, 278, 629: Coolant circulation pump relay | |
| S 400 Hybrid: Power electronics coolant circulation pump relay 2 | ||
| R | Cigarette lighter relay | |
| S | Engine 642 (except 642.8): Fuel pump relay | |
| Engines 642.8, 651 (from June 1, 2011): A/C compressor magnetic clutch relay | ||
| S 400 Hybrid: Power electronics coolant circulation pump relay 1 | ||
| No. | Rating (A) | Protected Circuit / Component |
| 115 | 50 | Heated rear window |
| 116 | 10 | Engines 157, 275, 278: Charge air cooler circulation pump |
| Engine 156: Engine oil cooler circulation pump | ||
| S 400 Hybrid: Power electronics coolant circulation pump 2 | ||
| 117 | 15 | Rear cigarette lighter fuse |
| 118 | 30 | Engines 629, 642: Fuel delivery module (Fuel pump fuse) |
| 15 | S 400 Hybrid: Power electronics coolant circulation pump 1 | |
| 15 | Engines 642.8, 651 (from June 1, 2011): A/C compressor electromagnetic clutch | |
| 119 | 7.5 | Front center console control panel |
| 120 | - | Spare |
| 121 | 10 | Audio tuner control unit |
| 122 | 7.5 | COMAND control unit |
| 123 | 40 | W221: Front right reversible emergency tensioning retractor (ETR) |
| 124 | 40 | W221: Front left reversible emergency tensioning retractor (ETR) |
| 125 | 5 | Voice control system control unit (VCS / SBS) |
| 126 | 25 | Overhead control panel (OCP) |
| 127 | 30 | Lumbar support pump |
| Multicontour seat pneumatic pump | ||
| Dynamic seat pneumatic pump | ||
| 128 | 25 | Engines 156, 157, 272, 273, 275, 276, 278, 642: Fuel pump control unit |
| 129 | 25 | Universal Handy Interface (UHI) cellular phone module |
| 130 | 30 | Electric parking brake control unit |
| 131 | 7.5 | Rear window antenna amplifier module |
| 133 | 15 | Trailer recognition control unit |
| 5 | Rearview camera | |
| 134 | 15 | Luggage compartment 12V power outlet |
| 135 | 7.5 | Radar sensor control unit (SGR) |
| PARKTRONIC control unit (PTS) | ||
| 136 | 7.5 | Engine 642.8: AdBlue® control unit |
| 137 | 7.5 | From Sept 1, 2010: Rearview camera |
| 138 | 5 | Navigation processor (Taiwan, through Aug 31, 2010) |
| Emergency call system (eCall) module | ||
| TV/tuner connector (Japan) | ||
| 139 | 15 | Rear seat backrest refrigerator box |
| 140 | 15 | Rear cigarette lighter connector with ashtray illumination |
| 115V AC power outlet | ||
| 141 | 5 | Rearview camera control unit |
| Rearview camera power supply module | ||
| 142 | 7.5 | PARKTRONIC control unit (PTS) |
| Radar sensor control unit (SGR) | ||
| Video and radar sensor control unit (from Sept 1, 2010) | ||
| 143 | 25 | Rear seat control unit |
| 144 | 25 | |
| 145 | 20 | Trailer hitch socket (AHV, 13-pin) |
| 146 | 25 | Trailer recognition control unit |
| 147 | - | Spare |
| 148 | 25 | Panoramic sliding sunroof Terminal 30 connector block |
| 149 | 25 | Panoramic sliding sunroof control unit |
| 150 | 7.5 | Combination TV tuner (analog/digital) |
| TV/tuner connector (Japan) | ||
| 151 | 20 | Trailer recognition control unit |
| 152 | 25 | DC/AC inverter |
Passenger Compartment Fuse Boxes
There are three fuse distribution boxes located inside the passenger compartment.
Cockpit Fuse Box No. 1 (Left Side)
Located on the driver’s side, on the left end-face of the dashboard/instrument panel.
| Diagram | ||
|---|---|---|
|
||
| No. | Rating (A) | Protected Circuit / Component |
| 92 | 40 | Front left seat control unit |
| 93 | 7.5 | Supplemental Restraint System (SRS) control unit |
| Weight Sensing System (WSS) module (USA) | ||
| 94 | 5 | Multifunction camera |
| 95 | - | Spare |
| 96 | 5 | Tire Pressure Monitoring System (TPMS / RDK) |
| 97 | 7.5 | DVD player |
| 98 | - | Spare |
| 99 | 7.5 | COMAND display unit |
| SPLITVIEW dual-view display | ||
| 10 | 5 | Media Interface control unit |
| 101 | 10 | W221: Left and right rear entertainment displays |
| 102 | 40 | Front right seat control unit |
| 103 | 7.5 | Electronic Stability Program (ESP) |
| 104 | 40 | Audio tuner control unit |
| 105 | - | Spare |
| 106 | 5 | Navigation processor |
| Electronic Toll Collection (ETC) module (Japan) | ||
| TV/tuner connector (South Korea) | ||
| 107 | 5 | Satellite Radio (SDARS) control unit |
| Digital Audio Broadcasting (DAB) module | ||
| HD Radio tuner module | ||
| 108 | 5 | Rear climate control unit |
| 109 | 15 | Rear climate control blower regulator |
| 110 | 7.5 | Left and right rear multicontour seat control unit |
| 111 | 5 | Rear center console switch group (HBF) |
| 112 | 5 | S 400 Hybrid: Front Signal Acquisition and Actuation Module (SAM) |
| 113 | 5 | S 400 Hybrid: DC/DC converter control unit |
Cockpit Fuse Box No. 2 (Right Side)
Located on the passenger’s side, on the right end-face of the dashboard/instrument panel.
| Diagram | ||
|---|---|---|
|
||
| No. | Rating (A) | Protected Circuit / Component |
| 70 | 40 | C216: Right door control unit |
| W221: Front right door control unit | ||
| 71 | 15 | KEYLESS-GO control unit |
| 72 | 7.5 | S 400 Hybrid: High-voltage pyrotechnic disconnect element |
| 73 | 5 | COMAND system (Japan) |
| Emergency call system (eCall) | ||
| 74 | 30 | Remote trunk closing system (HDS) |
| 75 | 10 | S 400 Hybrid: |
| High-voltage battery management system | ||
| Power electronics control unit | ||
| 76 | - | Engine 642.8: AdBlue delivery relay |
| 15 | S 400 Hybrid: Vacuum pump relay (+) | |
| 77 | 50 | Audio system amplifier (Sound system) |
| 78 | 25 | S 65 AMG (Engine 275): Auxiliary fan relay |
| Engine 642.8: AdBlue delivery relay | ||
| 15 | Engines 157, 278, S 400 Hybrid, CL 63 AMG: Charge air cooler circulation pump | |
| 79 | 7.5 | Anti-theft alarm siren |
| 80 | 40 | C216: Left door control unit |
| W221: Front left door control unit | ||
| 81 | 30 | C216: Rear passenger compartment control unit |
| 40 | W221: Rear left door control unit | |
| 82 | 30 | C216: Rear passenger compartment control unit |
| 40 | W221: Rear right door control unit | |
| 83 | 30 | DIRECT SELECT gear selector actuator module |
| 84 | 20 | Digital Sound Processor (DSP) |
| 85 | 10 | AMG models: Illuminated door sill plates |
| 86-89 | - | Spare |
| 90 | 20 | C216: Stationary heater (STH) |
| W221: Stationary heater (STH) or auxiliary heater booster (ZUH) | ||
| 91 | 5 | Stationary heater (STH) radio remote control receiver |
| S 400 Hybrid: Front SAM control unit | ||
Interior Pre-Fuse Box (F32/4)
Diagram of the cabin power pre-fuse block components.
|
||
| No. | Rating (A) | Protected Circuit / Component |
| 2 | 400 | Generator/Alternator (G2) |
| 3 | 150 | Electrohydraulic power steering (EHPS) |
| Engines 629, 642: Glow plug control unit | ||
| 4 | - | Interior pre-fuse box (F32/4) |
| 5 | 100 | Radiator/AC electric cooling fan with integrated output stage |
| 6 | 150 | Front SAM control unit with fuse and relay module |
| 7 | 40 | Electronic Stability Program (ESP) |
| S 400 Hybrid : Regenerative braking system | ||
| 8 | 25 | Electronic Stability Program (ESP) |
| S 400 Hybrid : Regenerative braking system | ||
| 9 | 25 | Front SAM control unit |
| 10 | - | Spare |
| F32/4k2 – Quiescent current cutout relay | ||
Engine Compartment Fuse Boxes
There are two distribution boxes in the engine compartment. The main fuse and relay box (N10/1) is located on the left side behind the protective partition wall cover.
Main Engine Compartment Fuse Box (N10/1)
Example view of main fuse box N10/1.
| Diagram | ||
|---|---|---|
|
||
| No. | Relay Designation | |
| A | Secondary air injection pump relay | |
| B | AIRMATIC air suspension compressor relay | |
| C | Terminal 87 engine circuit relay | |
| D | Terminal 15 circuit relay | |
| E | Terminal 87 chassis circuit relay | |
| F | Horn relay | |
| G | Terminal 15R relay | |
| H | Terminal 50 starter relay | |
| J | Terminal 15 starter circuit relay | |
| K | Heated windshield washer park area relay | |
| No. | Rating (A) | Protected Circuit / Component |
| 20 | 10 | Engines 629, 642, 651: CDI (Diesel) control unit |
| Engines 156, 157, 272, 273, 275, 276, 278: ME (Gasoline) control unit | ||
| 21 | 20 | Engines 156, 157, 272, 273, 275, 276, 278: Terminal 87 M1i circuit |
| Engines 629, 642: | ||
| CDI system | ||
| Fuel pump relay | ||
| Engine 651: Fuel metering valve | ||
| 22 | 15 | Engines 156, 157, 272, 273, 276, 278: Terminal 87 circuit |
| 23 | 20 | Engines 156, 157, 272, 273, 275, 276, 278, 629, 642: Terminal 87 circuit |
| Engines 156, 157, 272, 273, 276, 278: Terminal 87 M2e circuit | ||
| Engine 275: Terminal 87 M2i circuit terminal lug | ||
| Engine 651: Rear SAM control unit | ||
| 24 | 25 | Engines 157, 272, 273, 276, 278: Terminal 87 M1e circuit |
| Engine 642: CDI control unit | ||
| 25 | 7.5 | Instrument cluster |
| 26 | 10 | Left headlamp |
| 27 | 10 | Right headlamp |
| 28 | 7.5 | Engine 275: |
| Electronic transmission control unit (EGS) | ||
| Fully integrated transmission control unit (VGS) | ||
| 29 | 5 | Rear SAM control unit |
| 30 | 7.5 | Engines 629, 642, 651: CDI control unit |
| Engines 156, 157, 272, 273, 275, 276, 278: | ||
| ME control unit | ||
| Fuel pump control unit | ||
| 31 | 5 | S 400 Hybrid: Electric A/C compressor |
| 32 | 15 | Transmission auxiliary oil pump control unit |
| 33 | 5 | From Sept 1, 2010: ESP control unit |
| S 400 Hybrid: | ||
| High-voltage battery control unit | ||
| DC/DC converter control unit | ||
| Power electronics control unit | ||
| 34 | 5 | S 400 Hybrid: Regenerative braking control unit |
| 35 | 5 | Electric parking brake control unit |
| 36 | 10 | OBD-II diagnostic connector |
| 37 | 7.5 | Electronic ignition switch (EZS / EIS) |
| 38 | 7.5 | Central gateway module (CGW / ZGW) |
| 39 | 7.5 | Instrument cluster |
| 40 | 7.5 | Upper control panel (UCP) |
| 41 | 30 | Passenger-side windshield wiper motor |
| 42 | 30 | Driver-side / Main windshield wiper motor |
| 43 | 15 | Front cigarette lighter fuse |
| 44 | - | Spare |
| 45 | 5 | S 400 Hybrid: |
| Power electronics coolant circulation pump 1 | ||
| 46 | 15 | Active Body Control (ABC) |
| AIRMATIC suspension with Adaptive Damping System (ADS) | ||
| 47 | 15 | Steering column vertical adjustment motor |
| 48 | 15 | Steering column reach adjustment motor |
| 49 | 10 | Steering column module (SCM / MRM) |
| 50 | 15 | Automatic climate control unit (KLA) |
| 51 | 5 | COMAND display unit |
| SPLITVIEW dual-view display | ||
| 52a | 15 | C216: Horn (high/low tone) |
| 52b | 15 | W221, C216: Horn (high/low tone) |
| 53 | - | Spare |
| 54 | 40 | Climate control recirculation blower motor |
| 55 | 60 | Gasoline engines: Secondary air injection pump |
| 56 | 40 | AIRMATIC air suspension compressor |
| 57 | 30 | Heated windshield washer park area |
| 60 | 5 | Electrohydraulic power steering (EHPS) |
| 61 | 7.5 | Supplemental Restraint System (SRS) |
| 62 | 5 | Night View Assist control unit |
| 63 | 15 | Engines 629, 642 (from Sept 1, 2008): Fuel filter water separator sensor with heating element |
| 64 | 10 | NECK-PRO active head restraint solenoids (driver and front passenger seats) |
| 65 | 15 | From June 1, 2009: 12V power outlet in glove compartment |
| 66 | DISTRONIC radar control unit (DTR) | |
Engine Compartment Pre-Fuse Box (F32/3)
Located on the right side of the engine compartment near the battery is a pre-fuse module containing high-current fusible links.
| Diagram | ||
|---|---|---|
|
||
| No. | Rating (A) | Protected Circuit / Component |
| 3 | 150 | Rear SAM control unit with fuse and relay module |
| 4 | 150 | ECO Start-Stop function relay |
| S 400 Hybrid: DC/DC converter module | ||
| Heated windshield | ||
| 5 | 125 | Special vehicle multifunction control unit (MSS) |
| 40 | S 400 Hybrid : Electric vacuum pump | |
| 6 | 80 | Interior fuse box |
| 7 | 150 | Special vehicle multifunction control unit (MSS) |
| Engines 629, 642, 651: PTC auxiliary heater | ||
| 8 | 80 | Front SAM control unit with fuse and relay module |
| 9 | 80 | Left passenger compartment fuse box |
| 10 | 150 | Trunk SAM control unit with fuse and relay module |